How the product(s) are preparedPlasma is one of the three components of blood and contains all of the clotting factors found in blood. From plasma, many different products are made, whether it is fresh frozen plasma or when the plasma is divided into its different components. Plasma is obtained from volunteer donors who only donate plasma via an apheresis machine or who donate whole blood which is then centrifuged to separate the plasma from the rest of the blood. Part of the plasma obtained is used to make fresh frozen plasma (FFP). ) or cryoprecipitate. The cryoprecipitate contains fibrinogen and factor VIII is formed from the thawing of fresh frozen plasma. The majority of all donated plasma passes through a plasma fractionation machine. This machine divides the plasma into its different components and products produced are: • Intragram • Immunoglobulin • Anti-D • Albumin • Factor VIII • Prothrombinex (Factors II, IX and X) Major uses and advantages Cryoprecipitate is used for patients who do not don't have enough or are unable to produce enough fibrinogen and clotting factor VIII. Both FFP and cryoprecipitate can be used for liver transplant patients and for trauma cases in which patients have clotting problems. Other products such as immunoglobulins are used to fight diseases using antibodies present in plasma. Anti-D is used during pregnancies in cases of RhD incompatibility between the baby and the mother; this prevents the mother from creating antibodies against the baby. Albumin and clotting factors are used in patients with a deficiency of these proteins.How the quality and safety of blood products are maintainedAll manufactured products must be kept in...... middle of paper... ... matter in which phase the blood is can be traced. A small sample is also saved for future reference if necessary. For red blood cell bags, they must be refrigerated and stored between 4°C and 8°C. If the temperature falls outside this range, the cells will lose their integrity. How the product(s) are preparedPlatelets like plasma and red blood cells are collected from whole blood by centrifugation. But the main method of collecting platelets is apheresis. As the blood is collected, it is centrifuged and the platelets are collected in bags and the rest of the blood is then transfused to the donor. The process can take up to an hour, but these donations can be made at 2-4 week intervals as the red blood cells are returned to the donor.Main Uses and BenefitsHow the quality and safety of blood products is maintained