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  • Essay / Ergotism - 1491

    The symptoms described in this case, such as headaches, skin irritations, painful cramps and seizures, are all common in a condition known as ergotism. Ergotism is caused by the ingestion of alkaloids (ergotamines) produced by the fungus Claviceps purpurea (C. purpurea), which primarily infects Secale (rye) and other cereal grains. This results in ergot poisoning (Alderman et al., 1999). All Claviceps species are given the general term ergot and the majority of Claviceps species are restricted to one or more grass genera. The exception is common ergot caused by C. purpurea, which contains a host range exceeding 200 grass species (Alderman et al., 1999). C. purpurea, unlike other Claviceps species, is widespread worldwide and can survive in climates with different temperatures (including colder locations such as southern England), further suggesting that this is the most likely causative agent. Ergotism can be divided into two groups of symptoms. , convulsive and gangrenous. Convulsive ergotism is usually characterized by nerve dysfunction such as a twisted neck, which was formerly reported as seizures. The fact that many people died from gangrene clearly suggests that the ergotism experienced was not convulsive, because the symptoms of gangrene were not present. Gangrene develops when the blood supply is cut off to the affected part (ischemia) due to infection, trauma or vascular disease, with the most common sites being the fingers, toes and hands. This further suggests that it is gangrenous ergotism, which can be confirmed by physical examination of the patient and blood tests. A CT scan or MRI can help determine the amount of gas present and the extent of tissue damage. However, these tests were obviously not in the middle of a paper. Millions of them were carried out in children under 5 years old (Epidemiological Record, 2007). In patients in developing countries like Cameroon, invasive pneumococcal pneumonia has a high mortality rate (WHOInt, 2003). In terms of treatment and prophylaxis, appropriate antibiotics can help treat S. pneumoniae infections via outpatient treatment. Before antibiotic treatment, steroids may be given to children older than 6 weeks with possible pneumococcal meningitis and should be administered before or at the time of the first dose of antibiotics (Pickering et al,.2009). The use of penicillin, ceftriaxone, or ampicillin sulbactam is generally appropriate in hospitalized children; treatment should take into account local resistance patterns. Immunocompromised children with suspected pneumococcal pneumonia should take vancomycin and broad-spectrum cephalosporins..