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Essay / Kidney disease: Poststreptococcal glomerulonephritis Iturbe et al., 2008). . Poststreptococcal glomerulonephritis is considered an immune complex disease because glomerular damage results from interactions between antigen-antibody complexes and the complement system. Potential antigens that form the antigen-antibody complex are nephritic plasmin-binding protein, nephritic stemness-associated protein, and endostreptosin (Stickler, 2003). which is then deposited subendothelially along the basement membrane by reacting with the complement system. The complement cascade then promotes phagocytosis and digestive activity at the basement membrane, which directs fragmentation and degradation, thus leading to characteristic findings for a patient with poststreptococcal glomerulonephritis (Stickler, 2003)....
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